Status:
Ongoing
Project number:
#106
Effectiveness safety sotrovimab molnupiravir
Effectiveness safety sotrovimab molnupiravir is an OpenSAFELY project from The London School of Hygiene & Tropical Medicine. Every time a researcher runs their analytic code against patient data, it is audited in public here.
Project Ongoing
This study aims to examine and compare the effectiveness of sotrovimab and molnupiravir, the two most frequently prescribed medications by CMDUs so far, in non-hospitalised high-risk adult patients with COVID-19 across England. The main comparator groups are patients who received sotrovimab vs. those who received molnupiravir, between whom the risk of COVID-19 related hospitalisation/death within 29 days after treatment initiation (and other efficacy/safety outcomes of interest) will be compared.
Main results: https://www.bmj.com/content/379/bmj-2022-071932
In addition NICE requested an analysis: https://github.com/opensafely/sotrovimab-and-molnupiravir/tree/main/docs
Workspaces
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- GitHub repository:
- Safety-Sotrovimab-Paxlovid-Molnupiravir
- Git branch:
- main
- Created at:
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- GitHub repository:
- sotrovimab-and-molnupiravir
- Git branch:
- main
- Created at:
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- GitHub repository:
- sotrovimab-and-molnupiravir
- Git branch:
- main
- Created at:
Project timeline
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Project created:
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Code first run:
Why was the project created after code was first run?
The concept of projects were added to this site after workspaces, so this workspace predates its project.
Reports
Recently published reports
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No reports
This project does not currently have any published reports
Researchers
- Bang Zheng
- Katie Bechman
- Millie Green
- Ruth Costello