Coverage, effectiveness and safety of neutralising monoclonal antibodies or antivirals for non-hospitalised patients with COVID-19
Coverage, effectiveness and safety of neutralising monoclonal antibodies or antivirals for non-hospitalised patients with COVID-19 is an OpenSAFELY project from Bennett Institute. Every time a researcher runs their analytic code against patient data, it is audited in public here.
Project Ongoing
Links to papers and reports:
[1] https://bmjmedicine.bmj.com/content/2/1/e000276
Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descriptive cohort study of 23.4 million people in OpenSAFELY
[2] https://www.medrxiv.org/content/10.1101/2023.01.20.23284849v1
Comparative effectiveness of Paxlovid versus sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in non-hospitalised patients: observational cohort study using the OpenSAFELY platform
[3] https://reports.opensafely.org/reports/antivirals-and-nmabs-for-non-hospitalised-covid-19-patients-coverage-report/
Antivirals and nMABs for non-hospitalised COVID-19 patients: coverage report
Workspaces
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- GitHub repository:
- antibody-and-antiviral-deployment
- Git branch:
- main
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- GitHub repository:
- antibody-and-antiviral-deployment
- Git branch:
- report
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- GitHub repository:
- Paxlovid-and-sotrovimab
- Git branch:
- main
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- GitHub repository:
- Paxlovid_sotrovimab_molnupiravir_followup
- Git branch:
- main
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- GitHub repository:
- pax-non-users
- Git branch:
- main
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- GitHub repository:
- prophy_effects_Sotro_Molnup
- Git branch:
- main
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- GitHub repository:
- antibody-and-antiviral-deployment
- Git branch:
- check-exclusion-criteria
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- GitHub repository:
- antibody-and-antiviral-deployment
- Git branch:
- code-counts
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- GitHub repository:
- antibody-and-antiviral-deployment
- Git branch:
- draft-report
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- GitHub repository:
- antibody-and-antiviral-deployment
- Git branch:
- helen-edits2
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- GitHub repository:
- antibody-and-antiviral-deployment
- Git branch:
- helen-edits
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- GitHub repository:
- antibody-and-antiviral-deployment
- Git branch:
- outcomes
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- GitHub repository:
- antibody-and-antiviral-deployment
- Git branch:
- sgtf
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- GitHub repository:
- covid-therapeutics-notebook
- Git branch:
- main
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- GitHub repository:
- antibody-and-antiviral-deployment
- Git branch:
- mabs-and-antivirals
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Project timeline
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Project created:
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Code first run:
Why is the code first run date before the project created date?
In OpenSAFELY Jobs, code is run within a workspace. The workspaces feature was introduced before the projects feature, meaning that in some cases, workspaces were created before projects.
Outputs
Reports
Recently published reports
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No reports
This project does not currently have any published reports
Researchers
- Alain Amstutz
- Alex Walker
- Bang Zheng
- Brian Mackenna (Gmail)
- Daniel Grint
- Ed Parker
- Helen Curtis
- John Tazare
- Laurie Tomlinson
- Linda Nab
- Millie Green
- Qing Wen
- Rose Higgins
- Ruth Costello