Status:
Ongoing
paper/report linked
Project number:
#12
Investigating events following SARS-CoV-2 infection
Investigating events following SARS-CoV-2 infection is an OpenSAFELY project from University of Bristol. Every time a researcher runs their analytic code against patient data, it is audited in public here.
Project Ongoing - paper/report linked
COVID-19 infection may increase the chances of certain conditions, such as heart attacks and stroke. We used the OpenSAFELY platform to systematically investigate whether this is the case across disease areas. Specifically, we compared the number of people with COVID-19 infection who also have a record of one of these conditions against the number of people without COVID-19 infection who also have a record of one of these conditions. This allowed us to estimate how much COVID-19 infection increases the risk of these conditions. Our work may inform whether people with COVID-19 infection should be offered preventative treatments to protect against these conditions.
Our work on the following disease areas is publicly available:
Cardiovascular (code) (publication)
Diabetes (code) (preprint)
Mental health (code) (preprint)
Work is ongoing on the following disease areas:
Gastrointestinal (code)
Autoimmune (code)
Neurodegenerative (code)
Renal (code)
Respiratory (code)
We also have ongoing methods work that uses our cardiovascular project as an examplar.
Workspaces
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- GitHub repository:
- post-covid-autoimmune
- Git branch:
- main
- Created at:
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- GitHub repository:
- post-covid-autoimmune
- Git branch:
- Explore_study_def
- Created at:
-
- GitHub repository:
- post-covid-autoimmune
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-cvd-methods-redux
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-diabetes
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-gastrointestinal
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-gi-bleeds
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-mentalhealth
- Git branch:
- rerun_dereg
- Created at:
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- GitHub repository:
- post-covid-neurodegenerative
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-neurodegenerative
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-renal
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-respiratory-incident-events
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-respiratory
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-diabetes
- Git branch:
- add-new-diabetes-analyses
- Created at:
-
- GitHub repository:
- post-covid-gastrointestinal
- Git branch:
- fix-coxipw-error
- Created at:
-
- GitHub repository:
- post-covid-gastrointestinal
- Git branch:
- fix-cox-ipw_3
- Created at:
-
- GitHub repository:
- post-covid-gastrointestinal
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-gastrointestinal
- Git branch:
- table2-turn-off-main-analysis
- Created at:
-
- GitHub repository:
- post-covid-bristol
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-cvd-methods
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-diabetes
- Git branch:
- make-diabetes-three-cohort-repo
- Created at:
-
- GitHub repository:
- post-covid-gastrointestinal
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-gastrointestinal
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-mentalhealth
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-mentalhealth
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-mentalhealth
- Git branch:
- main
- Created at:
-
- GitHub repository:
- post-covid-neurodegenerative
- Git branch:
- main
- Created at:
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- GitHub repository:
- post-covid-pre-vaccinated-cardiovascular
- Git branch:
- main
- Created at:
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- GitHub repository:
- post-covid-renal
- Git branch:
- main
- Created at:
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- GitHub repository:
- post-covid-respiratory
- Git branch:
- main
- Created at:
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- GitHub repository:
- post-covid-respiratory
- Git branch:
- main
- Created at:
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- GitHub repository:
- post-covid-unvaccinated
- Git branch:
- main
- Created at:
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- GitHub repository:
- post-covid-vaccinated
- Git branch:
- main
- Created at:
Project timeline
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Project created:
-
Code first run:
Why is the code first run date before the project created date?
In OpenSAFELY Jobs, code is run within a workspace. The workspaces feature was introduced before the projects feature, meaning that in some cases, workspaces were created before projects.
Public repos
- post-covid-autoimmune
- post-covid-bristol
- post-covid-cvd-methods
- post-covid-cvd-methods-redux
- post-covid-diabetes
- post-covid-gastrointestinal
- post-covid-mentalhealth
- post-covid-neurodegenerative
- post-covid-pre-vaccinated-cardiovascular
- post-covid-renal
- post-covid-respiratory
- post-covid-respiratory-incident-events
- post-covid-unvaccinated
- post-covid-vaccinated
Private repos
These repos are currently not publicly visible
In accordance with the Principles of OpenSAFELY we expect all code from all users to be made public.
However, some GitHub repositories may be private during the development stage of a project, which means any links to them from this site will return a '404 Not Found' error unless you are logged in and have the relevant permissions.
Researchers
- Alex Whitmarsh
- Elsie Horne
- Emily Eyles
- Emma Tarmey
- Genevieve Cezard
- Jose Ignacio Cuitun Coronado
- Kurt Taylor
- Marwa Al Arab
- Michael Gulley
- Rachel Denholm
- Rochelle Knight
- Scott Walter
- Venexia Walker
- Yinghui Wei